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A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses
The vaccinia virus (VACV) C6 protein has sequence similarities with the poxvirus family Pox_A46, involved in regulation of host immune responses, but its role is unknown. Here, we have characterized the C6 protein and its effects in virus replication, innate immune sensing and immunogenicity in vivo...
Autores principales: | García-Arriaza, Juan, Nájera, José Luis, Gómez, Carmen E., Tewabe, Nolawit, Sorzano, Carlos Oscar S., Calandra, Thierry, Roger, Thierry, Esteban, Mariano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164197/ https://www.ncbi.nlm.nih.gov/pubmed/21909386 http://dx.doi.org/10.1371/journal.pone.0024244 |
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