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SOD3 Decreases Ischemic Injury Derived Apoptosis through Phosphorylation of Erk1/2, Akt, and FoxO3a
BACKGROUND: Extracellular superoxide dismutase (SOD3), which dismutates superoxide anion to hydrogen peroxide, has been shown to reduce the free radical stress derived apoptosis in tissue injuries. Since both superoxide anion and hydrogen peroxide have a marked impact on signal transduction pathways...
Autores principales: | Laatikainen, Lilja E., Incoronato, Mariarosaria, Castellone, Maria Domenica, Laurila, Juha P., Santoro, Massimo, Laukkanen, Mikko O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164207/ https://www.ncbi.nlm.nih.gov/pubmed/21909393 http://dx.doi.org/10.1371/journal.pone.0024456 |
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