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Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes
OBJECTIVE: The aim of this study was to evaluate the effect of organic grape juice intake on biochemical variables and microcirculatory parameters in triathlon athletes. INTRODUCTION: The physiological stress that is imposed by a strenuous sport, such as a triathlon, together with an insufficient am...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164400/ https://www.ncbi.nlm.nih.gov/pubmed/22179155 http://dx.doi.org/10.1590/S1807-59322011000900005 |
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author | Gonçalves, Mariana Correa Bezerra, Flavia Fioruci de Araujo Eleutherio, Elis Cristina Bouskela, Eliete Koury, Josely |
author_facet | Gonçalves, Mariana Correa Bezerra, Flavia Fioruci de Araujo Eleutherio, Elis Cristina Bouskela, Eliete Koury, Josely |
author_sort | Gonçalves, Mariana Correa |
collection | PubMed |
description | OBJECTIVE: The aim of this study was to evaluate the effect of organic grape juice intake on biochemical variables and microcirculatory parameters in triathlon athletes. INTRODUCTION: The physiological stress that is imposed by a strenuous sport, such as a triathlon, together with an insufficient amount of antioxidants in the diet may cause oxidative imbalance and endothelial dysfunction. METHODS: Ten adult male triathletes participated in this study. A venous blood sample was drawn before (baseline) and after 20 days of organic grape juice intake (300 ml/day). Serum insulin, plasma glucose and uric acid levels, the total content of polyphenols, and the erythrocyte superoxide dismutase activity were determined. The functional microcirculatory parameters (the functional capillary density, red blood cell velocity at baseline and peak levels, and time required to reach the peak red blood cell velocity during postocclusive reactive hyperemia after a one-min arterial occlusion) were evaluated using nailfold videocapillaroscopy. RESULTS: Compared with baseline levels, the peak levels of serum insulin (p = 0.02), plasma uric acid (p = 0.04), the functional capillary density (p = 0.003), and the red blood cell velocity (p<0.001) increased, whereas the plasma glucose level (p<0.001), erythrocyte superoxide dismutase activity (p = 0.04), and time required to reach red blood cell velocity during postocclusive reactive hyperemia (p = 0.04) decreased after organic grape juice intake. CONCLUSION: Our data showed that organic grape juice intake improved glucose homeostasis, antioxidant capacity, and microvascular function, which may be due to its high concentration of polyphenols. These results indicate that organic grape juice has a positive effect in endurance athletes. |
format | Online Article Text |
id | pubmed-3164400 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-31644002011-09-02 Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes Gonçalves, Mariana Correa Bezerra, Flavia Fioruci de Araujo Eleutherio, Elis Cristina Bouskela, Eliete Koury, Josely Clinics (Sao Paulo) Clinical Science OBJECTIVE: The aim of this study was to evaluate the effect of organic grape juice intake on biochemical variables and microcirculatory parameters in triathlon athletes. INTRODUCTION: The physiological stress that is imposed by a strenuous sport, such as a triathlon, together with an insufficient amount of antioxidants in the diet may cause oxidative imbalance and endothelial dysfunction. METHODS: Ten adult male triathletes participated in this study. A venous blood sample was drawn before (baseline) and after 20 days of organic grape juice intake (300 ml/day). Serum insulin, plasma glucose and uric acid levels, the total content of polyphenols, and the erythrocyte superoxide dismutase activity were determined. The functional microcirculatory parameters (the functional capillary density, red blood cell velocity at baseline and peak levels, and time required to reach the peak red blood cell velocity during postocclusive reactive hyperemia after a one-min arterial occlusion) were evaluated using nailfold videocapillaroscopy. RESULTS: Compared with baseline levels, the peak levels of serum insulin (p = 0.02), plasma uric acid (p = 0.04), the functional capillary density (p = 0.003), and the red blood cell velocity (p<0.001) increased, whereas the plasma glucose level (p<0.001), erythrocyte superoxide dismutase activity (p = 0.04), and time required to reach red blood cell velocity during postocclusive reactive hyperemia (p = 0.04) decreased after organic grape juice intake. CONCLUSION: Our data showed that organic grape juice intake improved glucose homeostasis, antioxidant capacity, and microvascular function, which may be due to its high concentration of polyphenols. These results indicate that organic grape juice has a positive effect in endurance athletes. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011-09 /pmc/articles/PMC3164400/ /pubmed/22179155 http://dx.doi.org/10.1590/S1807-59322011000900005 Text en Copyright © 2011 Hospital das Clínicas da FMUSP http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Science Gonçalves, Mariana Correa Bezerra, Flavia Fioruci de Araujo Eleutherio, Elis Cristina Bouskela, Eliete Koury, Josely Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes |
title | Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes |
title_full | Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes |
title_fullStr | Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes |
title_full_unstemmed | Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes |
title_short | Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes |
title_sort | organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes |
topic | Clinical Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164400/ https://www.ncbi.nlm.nih.gov/pubmed/22179155 http://dx.doi.org/10.1590/S1807-59322011000900005 |
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