Cargando…

Translocation channel gating kinetics balances protein translocation efficiency with signal sequence recognition fidelity

The transition between the closed and open conformations of the Sec61 complex permits nascent protein insertion into the translocation channel. A critical event in this structural transition is the opening of the lateral translocon gate that is formed by four transmembrane (TM) spans (TM2, TM3, TM7,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Trueman, Steven F., Mandon, Elisabet C., Gilmore, Reid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164448/ https://www.ncbi.nlm.nih.gov/pubmed/21737680 http://dx.doi.org/10.1091/mbc.E11-01-0070

Ejemplares similares

A gating motif in the translocation channel sets the hydrophobicity threshold for signal sequence function
por: Trueman, Steven F., et al.
Publicado: (2012)

An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation
por: Jiang, Ying, et al.
Publicado: (2008)

Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation
por: Cheng, Zhiliang, et al.
Publicado: (2005)

Rapid inactivation of the yeast Sec complex selectively blocks transport of post-translationally translocated proteins
por: Yi, Jae Kyo, et al.
Publicado: (2021)

Asparagine-linked glycosylation is not directly coupled to protein translocation across the endoplasmic reticulum in Saccharomyces cerevisiae
por: Shrimal, Shiteshu, et al.
Publicado: (2019)

Dual recognition of the ribosome and the signal recognition particle by the SRP receptor during protein targeting to the endoplasmic reticulum
por: Mandon, Elisabet C., et al.
Publicado: (2003)

Translocation and fidelity of Escherichia coli RNA polymerase
por: Nedialkov, Yuri A., et al.
Publicado: (2013)

Azoospermia and reciprocal translocations: should whole-exome sequencing be recommended?
por: Ghieh, Farah, et al.
Publicado: (2021)

Ion Conductivity of the Bacterial Translocation Channel SecYEG Engaged in Translocation
por: Knyazev, Denis G., et al.
Publicado: (2014)

Signal Sequence Recognition in Cotranslational Translocation by Protein Components of the Endoplasmic Reticulum Membrane
por: Mothes, Walther, et al.
Publicado: (1998)

The signal sequence receptor, unlike the signal recognition particle receptor, is not essential for protein translocation
Publicado: (1992)

Using short read sequencing to characterise balanced reciprocal translocations in pigs
por: Bouwman, Aniek C., et al.
Publicado: (2020)

Logic Gate Operation by DNA Translocation through Biological Nanopores
por: Yasuga, Hiroki, et al.
Publicado: (2016)

Gene sequencing and result analysis of balanced translocation carriers by third-generation gene sequencing technology
por: Zeng, Xiaoqi, et al.
Publicado: (2023)

C-banding in sheep with balanced homolog interchromosomal translocation
por: Glahn-Luft, B, et al.
Publicado: (1977)

Location of Balanced Chromosome-Translocation Breakpoints by Long-Read Sequencing on the Oxford Nanopore Platform
por: Hu, Liang, et al.
Publicado: (2020)

Identification of a translocated gating charge in a voltage-dependent channel. Colicin E1 channels in planar phospholipid bilayer membranes
Publicado: (1991)

Use of genetically encoded, light-gated ion translocators to control tumorigenesis
por: Chernet, Brook T., et al.
Publicado: (2016)

Structure of the SecY channel during initiation of protein translocation
por: Park, Eunyong, et al.
Publicado: (2013)

Problem-Elephant Translocation: Translocating the Problem and the Elephant?
por: Fernando, Prithiviraj, et al.
Publicado: (2012)

Connecting the Kinetics and Energy Landscape of tRNA Translocation on the Ribosome
por: Whitford, Paul C., et al.
Publicado: (2013)

Programmed –1 Frameshifting by Kinetic Partitioning during Impeded Translocation
por: Caliskan, Neva, et al.
Publicado: (2014)

A strategy for generation and balancing of autosome: Y chromosome translocations
por: Joshi, Sonal S, et al.
Publicado: (2014)

Balanced Reciprocal Translocation: Multiple Chromosome Rearrangements in an Infertile Female
por: Gupta, Neelam, et al.
Publicado: (2019)

Sizing the Protein Translocation Pathway of Colicin Ia Channels
por: Kienker, Paul K., et al.
Publicado: (2003)

Tailoring particle translocation via dielectrophoresis in pore channels
por: Tanaka, Shoji, et al.
Publicado: (2016)

Identifying Balanced Chromosomal Translocations in Human Embryos by Oxford Nanopore Sequencing and Breakpoints Region Analysis
por: Pei, Zhenle, et al.
Publicado: (2022)

SecY-mediated quality control prevents the translocation of non-gated porins
por: Jung, Sebastian, et al.
Publicado: (2020)

Genomic Comparison of Translocating and Non-Translocating Escherichia coli
por: Bachmann, Nathan L., et al.
Publicado: (2015)

Structural basis of substrate recognition and translocation by human ABCA4
por: Xie, Tian, et al.
Publicado: (2021)

Transmembrane protein rotaxanes reveal kinetic traps in the refolding of translocated substrates
por: Feng, Jianfei, et al.
Publicado: (2020)

Accessory signals in protein translocation
por: Hansen, Katja G., et al.
Publicado: (2018)

Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function
por: Thomson, Pippa A, et al.
Publicado: (2016)

A Study on Balanced Chromosomal Translocations in Couples with Recurrent Pregnancy Loss
por: Priya, Pritti K., et al.
Publicado: (2018)

Complete maturation of the plastid protein translocation channel requires a type I signal peptidase
por: Inoue, Kentaro, et al.
Publicado: (2005)

BasePhasing: a highly efficient approach for preimplantation genetic haplotyping in clinical application of balanced translocation carriers
por: Zhang, Shuo, et al.
Publicado: (2019)

Role of the Cytoplasmic Segments of Sec61α in the Ribosome-Binding and Translocation-Promoting Activities of the Sec61 Complex
por: Raden, David, et al.
Publicado: (2000)

GTPase domain of the 54-kD subunit of the mammalian signal recognition particle is required for protein translocation but not for signal sequence binding
Publicado: (1993)

Mechanisms and consequences of gut commensal translocation in chronic diseases
por: Fine, Rebecca L., et al.
Publicado: (2019)

Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots
por: Wu, Bo, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pmj54rkhujjjinq1o8fu048ft4