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Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides

Mannose-6-phosphate (M6P) is an essential precursor for mannosyl glycoconjugates, including lipid-linked oligosaccharides (LLO; glucose(3)mannose(9)GlcNAc(2)-P-P-dolichol) used for protein N-glycosylation. In permeabilized mammalian cells, M6P also causes specific LLO cleavage. However, the context...

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Detalles Bibliográficos
Autores principales:	Gao, Ningguo, Shang, Jie, Huynh, Dang, Manthati, Vijaya L., Arias, Carolina, Harding, Heather P., Kaufman, Randal J., Mohr, Ian, Ron, David, Falck, John R., Lehrman, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164449/ https://www.ncbi.nlm.nih.gov/pubmed/21737679 http://dx.doi.org/10.1091/mbc.E11-04-0286

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