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Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells

Genetic screens in Drosophila have identified regulators of endocytic trafficking as neoplastic tumor suppressor genes. For example, Drosophila endosomal sorting complex required for transport (ESCRT) mutants lose epithelial polarity and show increased cell proliferation, suggesting that ESCRT prote...

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Detalles Bibliográficos
Autores principales:	Dukes, Joseph D., Fish, Laura, Richardson, Judith D., Blaikley, Elizabeth, Burns, Samir, Caunt, Christopher J., Chalmers, Andrew D., Whitley, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164465/ https://www.ncbi.nlm.nih.gov/pubmed/21757541 http://dx.doi.org/10.1091/mbc.E11-04-0343

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