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The Trypanosoma cruzi Protease Cruzain Mediates Immune Evasion

Trypanosoma cruzi is the causative agent of Chagas' disease. Novel chemotherapy with the drug K11777 targets the major cysteine protease cruzain and disrupts amastigote intracellular development. Nevertheless, the biological role of the protease in infection and pathogenesis remains unclear as...

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Detalles Bibliográficos
Autores principales:	Doyle, Patricia S., Zhou, Yuan M., Hsieh, Ivy, Greenbaum, Doron C., McKerrow, James H., Engel, Juan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164631/ https://www.ncbi.nlm.nih.gov/pubmed/21909255 http://dx.doi.org/10.1371/journal.ppat.1002139

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