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Th2-polarised PrP-specific Transgenic T-cells Confer Partial Protection against Murine Scrapie

Several hurdles must be overcome in order to achieve efficient and safe immunotherapy against conformational neurodegenerative diseases. In prion diseases, the main difficulty is that the prion protein is tolerated as a self protein, which prevents powerful immune responses. Passive antibody therapy...

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Detalles Bibliográficos
Autores principales: Iken, Saci, Bachy, Véronique, Gourdain, Pauline, Lim, Annick, Grégoire, Sylvie, Chaigneau, Thomas, Aucouturier, Pierre, Carnaud, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164648/
https://www.ncbi.nlm.nih.gov/pubmed/21909267
http://dx.doi.org/10.1371/journal.ppat.1002216