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HTLV-1 Propels Thymic Human T Cell Development in “Human Immune System” Rag2(-/-) gamma c(-/-) Mice
Alteration of early haematopoietic development is thought to be responsible for the onset of immature leukemias and lymphomas. We have previously demonstrated that Tax(HTLV-1) interferes with ß-selection, an important checkpoint of early thymopoiesis, indicating that human T-cell leukemia virus type...
Autores principales: | Villaudy, Julien, Wencker, Mélanie, Gadot, Nicolas, Gillet, Nicolas A., Scoazec, Jean-Yves, Gazzolo, Louis, Manz, Markus G., Bangham, Charles R. M., Dodon, Madeleine Duc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164654/ https://www.ncbi.nlm.nih.gov/pubmed/21909275 http://dx.doi.org/10.1371/journal.ppat.1002231 |
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