Cargando…
PfMDR1: Mechanisms of Transport Modulation by Functional Polymorphisms
ATP-Binding Cassette (ABC) transporters are efflux pumps frequently associated with multidrug resistance in many biological systems, including malaria. Antimalarial drug-resistance involves an ABC transporter, PfMDR1, a homologue of P-glycoprotein in humans. Twenty years of research have shown that...
Autores principales: | Ferreira, Pedro Eduardo, Holmgren, Gabrielle, Veiga, Maria Isabel, Uhlén, Per, Kaneko, Akira, Gil, José Pedro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164660/ https://www.ncbi.nlm.nih.gov/pubmed/21912647 http://dx.doi.org/10.1371/journal.pone.0023875 |
Ejemplares similares
-
Expansion of a Specific Plasmodium falciparum PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport
por: Calçada, Carla, et al.
Publicado: (2020) -
Monitoring PfMDR1 transport in Plasmodium falciparum
por: Reiling, Sarah J, et al.
Publicado: (2015) -
PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs
por: van der Velden, Maarten, et al.
Publicado: (2015) -
PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers
por: Eastman, Richard T., et al.
Publicado: (2016) -
Assessment of Plasmodium falciparum PfMDR1 transport rates using Fluo-4
por: Friedrich, O, et al.
Publicado: (2014)