Imaging Long-Term Fate of Intramyocardially Implanted Mesenchymal Stem Cells in a Porcine Myocardial Infarction Model

The long-term fate of stem cells after intramyocardial delivery is unknown. We used noninvasive, repetitive PET/CT imaging with [(18)F]FEAU to monitor the long-term (up to 5 months) spatial-temporal dynamics of MSCs retrovirally transduced with the sr39HSV1-tk gene (sr39HSV1-tk-MSC) and implanted in...

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Detalles Bibliográficos
Autores principales: Perin, Emerson C., Tian, Mei, Marini, Frank C., Silva, Guilherme V., Zheng, Yi, Baimbridge, Fred, Quan, Xin, Fernandes, Marlos R., Gahremanpour, Amir, Young, Daniel, Paolillo, Vincenzo, Mukhopadhyay, Uday, Borne, Agatha T., Uthamanthil, Rajesh, Brammer, David, Jackson, James, Decker, William K., Najjar, Amer M., Thomas, Michael W., Volgin, Andrei, Rabinovich, Brian, Soghomonyan, Suren, Jeong, Hwan-Jeong, Rios, Jesse M., Steiner, David, Robinson, Simon, Mawlawi, Osama, Pan, Tinsu, Stafford, Jason, Kundra, Vikas, Li, Chun, Alauddin, Mian M., Willerson, James T., Shpall, Elizabeth, Gelovani, Juri G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164664/
https://www.ncbi.nlm.nih.gov/pubmed/21912635
http://dx.doi.org/10.1371/journal.pone.0022949

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