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Sequential Bottlenecks Drive Viral Evolution in Early Acute Hepatitis C Virus Infection
Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and liver disease. The characterization of viral populations that successfully initiate infection, and also those that drive progression to chronicity is instrumental for understanding pathogenesis and vaccine design....
Autores principales: | Bull, Rowena A., Luciani, Fabio, McElroy, Kerensa, Gaudieri, Silvana, Pham, Son T., Chopra, Abha, Cameron, Barbara, Maher, Lisa, Dore, Gregory J., White, Peter A., Lloyd, Andrew R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164670/ https://www.ncbi.nlm.nih.gov/pubmed/21912520 http://dx.doi.org/10.1371/journal.ppat.1002243 |
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