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Age-Dependent Recombination Rates in Human Pedigrees
In humans, chromosome-number abnormalities have been associated with altered recombination and increased maternal age. Therefore, age-related effects on recombination are of major importance, especially in relation to the mechanisms involved in human trisomies. Here, we examine the relationship betw...
Autores principales: | Hussin, Julie, Roy-Gagnon, Marie-Hélène, Gendron, Roxanne, Andelfinger, Gregor, Awadalla, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164683/ https://www.ncbi.nlm.nih.gov/pubmed/21912527 http://dx.doi.org/10.1371/journal.pgen.1002251 |
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