Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice

PURPOSE: Previous experiments from our laboratory showed that the oral intake of selected guanidino compounds could block the formation of crystallin-bound advanced ascorbylation products. Here we tested whether these were also active when applied as eye drops. METHODS: Two month old hSVCT2 transgen...

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Detalles Bibliográficos
Autores principales: Fan, Xingjun, Xiaoqin, Liu, Potts, Breshey, Strauch, Christopher M., Nemet, Ina, Monnier, Vincent M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164690/
https://www.ncbi.nlm.nih.gov/pubmed/21897744

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