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Elongator Complex Influences Telomeric Gene Silencing and DNA Damage Response by Its Role in Wobble Uridine tRNA Modification

Elongator complex is required for formation of the side chains at position 5 of modified nucleosides 5-carbamoylmethyluridine (ncm(5)U(34)), 5-methoxycarbonylmethyluridine (mcm(5)U(34)), and 5-methoxycarbonylmethyl-2-thiouridine (mcm(5)s(2)U(34)) at wobble position in tRNA. These modified nucleoside...

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Detalles Bibliográficos
Autores principales:	Chen, Changchun, Huang, Bo, Eliasson, Mattias, Rydén, Patrik, Byström, Anders S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164696/ https://www.ncbi.nlm.nih.gov/pubmed/21912530 http://dx.doi.org/10.1371/journal.pgen.1002258

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