The Novel Immunosuppressive Protein Kinase C Inhibitor Sotrastaurin Has No Pro-Viral Effects on the Replication Cycle of Hepatitis B or C Virus

The pan-protein kinase C (PKC) inhibitor sotrastaurin (AEB071) is a novel immunosuppressant currently in phase II trials for immunosuppression after solid organ transplantation. Besides T-cell activation, PKC affects numerous cellular processes that are potentially important for the replication of h...

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Detalles Bibliográficos
Autores principales: von Hahn, Thomas, Schulze, Andreas, Chicano Wust, Ivan, Heidrich, Benjamin, Becker, Thomas, Steinmann, Eike, Helfritz, Fabian A., Rohrmann, Katrin, Urban, Stephan, Manns, Michael P., Pietschmann, Thomas, Ciesek, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164709/
https://www.ncbi.nlm.nih.gov/pubmed/21909416
http://dx.doi.org/10.1371/journal.pone.0024142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164709/
https://www.ncbi.nlm.nih.gov/pubmed/21909416
http://dx.doi.org/10.1371/journal.pone.0024142

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