Cargando…

FUS/TLS Is a Co-Activator of Androgen Receptor in Prostate Cancer Cells

Androgen receptor (AR) is a member of the nuclear receptor family of transcription factors. Upon binding to androgens, AR becomes transcriptionally active to regulate the expression of target genes that harbor androgen response elements (AREs) in their promoters and/or enhancers. AR is essential for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haile, Simon, Lal, Aaron, Myung, Jae-Kyung, Sadar, Marianne D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164714/ https://www.ncbi.nlm.nih.gov/pubmed/21909421 http://dx.doi.org/10.1371/journal.pone.0024197

Ejemplares similares

TLS/FUS: A protein in cancer and ALS
por: Tan, Adelene Y., et al.
Publicado: (2012)

A Yeast Model of FUS/TLS-Dependent Cytotoxicity
por: Ju, Shulin, et al.
Publicado: (2011)

Non-Genomic Actions of the Androgen Receptor in Prostate Cancer
por: Leung, Jacky K., et al.
Publicado: (2017)

Inhibition of androgen receptor by decoy molecules delays progression to castration-recurrent prostate cancer
por: Myung, Jae-Kyung, et al.
Publicado: (2017)

ALS mutations in TLS/FUS disrupt target gene expression
por: Coady, Tristan H., et al.
Publicado: (2015)

Androgen receptor targeted therapies in castration‐resistant prostate cancer: Bench to clinic
por: Imamura, Yusuke, et al.
Publicado: (2016)

A loss of FUS/TLS function leads to impaired cellular proliferation
por: Ward, C L, et al.
Publicado: (2014)

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS
por: Sun, Zhihui, et al.
Publicado: (2011)

Functions of FUS/TLS From DNA Repair to Stress Response: Implications for ALS
por: Sama, Reddy Ranjith Kumar, et al.
Publicado: (2014)

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice
por: Kino, Yoshihiro, et al.
Publicado: (2016)

RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS
por: Hamad, Nesreen, et al.
Publicado: (2020)

FUS/TLS Suppresses Enterovirus Replication and Promotes Antiviral Innate Immune Responses
por: Xue, Yuan Chao, et al.
Publicado: (2021)

Enzalutamide and blocking androgen receptor in advanced prostate cancer: lessons learnt from the history of drug development of antiandrogens
por: Ito, Yusuke, et al.
Publicado: (2018)

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics
por: Baron, Desiree M, et al.
Publicado: (2013)

FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis
por: Kino, Yoshihiro, et al.
Publicado: (2015)

G-quadruplex binding ability of TLS/FUS depends on the β-spiral structure of the RGG domain
por: Yagi, Ryota, et al.
Publicado: (2018)

Ebp1 Sumoylation, Regulated by TLS/FUS E3 Ligase, Is Required for its Anti-proliferative Activity
por: Oh, Sang-Muk, et al.
Publicado: (2009)

Cyclin-dependent Kinase 4/6 Inhibitor Palbociclib in Combination with Ralaniten Analogs for the Treatment of Androgen Receptor–positive Prostate and Breast Cancers
por: Tien, Amy H., et al.
Publicado: (2022)

Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations
por: Kino, Yoshihiro, et al.
Publicado: (2011)

Targeting the N-Terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer
por: Antonarakis, Emmanuel S., et al.
Publicado: (2016)

Plastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA
por: Kondo, Keiko, et al.
Publicado: (2018)

The RNA-binding protein FUS/TLS interacts with SPO11 and PRDM9 and localize at meiotic recombination hotspots
por: Giannattasio, Teresa, et al.
Publicado: (2023)

Automatic Registration of TLS-TLS and TLS-MLS Point Clouds Using a Genetic Algorithm
por: Yan, Li, et al.
Publicado: (2017)

Combination therapy with androgen receptor N‐terminal domain antagonist EPI‐7170 and enzalutamide yields synergistic activity in AR‐V7‐positive prostate cancer
por: Hirayama, Yukiyoshi, et al.
Publicado: (2020)

PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage
por: Rulten, Stuart L., et al.
Publicado: (2014)

The Effect of PRMT1-Mediated Arginine Methylation on the Subcellular Localization, Stress Granules, and Detergent-Insoluble Aggregates of FUS/TLS
por: Yamaguchi, Atsushi, et al.
Publicado: (2012)

m(6)A Modified Short RNA Fragments Inhibit Cytoplasmic TLS/FUS Aggregation Induced by Hyperosmotic Stress
por: Yoneda, Ryoma, et al.
Publicado: (2021)

SSL and TLS
por: Oppliger, Rolf
Publicado: (2016)

DDIT3/CHOP and the sarcoma fusion oncoprotein FUS-DDIT3/TLS-CHOP bind cyclin-dependent kinase 2
por: Bento, Christoffer, et al.
Publicado: (2009)

ALS-causative mutations in FUS/TLS confer gain- and loss-of-function by altered association with SMN and U1-snRNP
por: Sun, Shuying, et al.
Publicado: (2015)

Characterization of Niphatenones that Inhibit Androgen Receptor N-Terminal Domain
por: Banuelos, Carmen A., et al.
Publicado: (2014)

rTLS: Secure and Efficient TLS Session Resumption for the Internet of Things †
por: Tange, Koen, et al.
Publicado: (2021)

FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors
por: Raczynska, Katarzyna Dorota, et al.
Publicado: (2015)

Changes in the Expression of FUS/TLS in Spinal Cords of SOD1 G93A Transgenic Mice and Correlation with Motor-Neuron Degeneration
por: Li, Jiao, et al.
Publicado: (2016)

Androgen Receptor Splice Variant 7 Drives the Growth of Castration Resistant Prostate Cancer without Being Involved in the Efficacy of Taxane Chemotherapy
por: Shimizu, Yasuomi, et al.
Publicado: (2018)

Ralaniten Sensitizes Enzalutamide-Resistant Prostate Cancer to Ionizing Radiation in Prostate Cancer Cells that Express Androgen Receptor Splice Variants
por: Banuelos, Carmen A., et al.
Publicado: (2020)

Turning Tertiary Lymphoid Structures (TLS) into Hot Spots: Values of TLS in Gastrointestinal Tumors
por: Cai, Daming, et al.
Publicado: (2023)

TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review
por: Zhang, Heyang, et al.
Publicado: (2022)

Androgen receptor co-regulation in prostate cancer
por: Senapati, Dhirodatta, et al.
Publicado: (2020)

SSL and TLS: Theory and Practice
por: Oppliger, Rolf
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_mfaf40of8utvo0rvi9mlfu6f8u