Molecular profiling indicates orthotopic xenograft of glioma cell lines simulate a subclass of human glioblastoma

Cell line models have been widely used to investigate glioblastoma multiforme (GBM) pathobiology and in the development of targeted therapies. However, GBM tumours are molecularly heterogeneous and how cell lines can best model that diversity is unknown. In this report, we investigated gene expressi...

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Detalles Bibliográficos
Autores principales: Shankavaram, Uma T, Bredel, Markus, Burgan, William E, Carter, Donna, Tofilon, Philip, Camphausen, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164941/
https://www.ncbi.nlm.nih.gov/pubmed/21595825
http://dx.doi.org/10.1111/j.1582-4934.2011.01345.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164941/
https://www.ncbi.nlm.nih.gov/pubmed/21595825
http://dx.doi.org/10.1111/j.1582-4934.2011.01345.x

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