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Molecular profiling indicates orthotopic xenograft of glioma cell lines simulate a subclass of human glioblastoma
Cell line models have been widely used to investigate glioblastoma multiforme (GBM) pathobiology and in the development of targeted therapies. However, GBM tumours are molecularly heterogeneous and how cell lines can best model that diversity is unknown. In this report, we investigated gene expressi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164941/ https://www.ncbi.nlm.nih.gov/pubmed/21595825 http://dx.doi.org/10.1111/j.1582-4934.2011.01345.x |