Laboratory-based Surveillance of Extensively Drug-Resistant Tuberculosis, China

To estimate the prevalence of extensively drug-resistant tuberculosis (XDR TB) in China, we retrospectively analyzed drug-resistance profiles of 989 clinical Mycobacterium tuberculosis isolates. We found 319 (32.3%) isolates resistant to >1 first-line drugs; 107 (10.8%) isolates were multidrug re...

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Detalles Bibliográficos
Autores principales: Deng, Yunfeng, Wang, Yan, Wang, Junling, Jing, Hui, Yu, Chunbao, Wang, Haiying, Liu, Zhimin, Graviss, Edward A., Ma, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2011
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165999/
https://www.ncbi.nlm.nih.gov/pubmed/21392442
http://dx.doi.org/10.3201/eid1703.100812
Descripción
Sumario:To estimate the prevalence of extensively drug-resistant tuberculosis (XDR TB) in China, we retrospectively analyzed drug-resistance profiles of 989 clinical Mycobacterium tuberculosis isolates. We found 319 (32.3%) isolates resistant to >1 first-line drugs; 107 (10.8%) isolates were multidrug resistant, of which 20 (18.7%) were XDR. XDR TB is of major concern in China.

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