Multidrug-Resistant Genotypes of Plasmodium falciparum, Myanmar

We performed a molecular epidemiologic survey of mutations associated with drug-resistance genes in Plasmodium falciparum in northeastern Myanmar. In this region, 3 highly mutated drug-resistance haplotypes and 1 associated with decreased quinine susceptibility were prevalent, which suggests that pa...

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Autores principales: Yang, Zhaoqing, Li, Chaoqun, Miao, Miao, Zhang, Zaixing, Sun, Xiaodong, Meng, Hao, Li, Jie, Fan, Qi, Cui, Liwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2011
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166001/
https://www.ncbi.nlm.nih.gov/pubmed/21392443
http://dx.doi.org/10.3201/eid1703.100870
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author Yang, Zhaoqing
Li, Chaoqun
Miao, Miao
Zhang, Zaixing
Sun, Xiaodong
Meng, Hao
Li, Jie
Fan, Qi
Cui, Liwang
author_facet Yang, Zhaoqing
Li, Chaoqun
Miao, Miao
Zhang, Zaixing
Sun, Xiaodong
Meng, Hao
Li, Jie
Fan, Qi
Cui, Liwang
author_sort Yang, Zhaoqing
collection PubMed
description We performed a molecular epidemiologic survey of mutations associated with drug-resistance genes in Plasmodium falciparum in northeastern Myanmar. In this region, 3 highly mutated drug-resistance haplotypes and 1 associated with decreased quinine susceptibility were prevalent, which suggests that parasites may be resistant to multiple commonly used antimalarial drugs.
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spelling pubmed-31660012011-11-15 Multidrug-Resistant Genotypes of Plasmodium falciparum, Myanmar Yang, Zhaoqing Li, Chaoqun Miao, Miao Zhang, Zaixing Sun, Xiaodong Meng, Hao Li, Jie Fan, Qi Cui, Liwang Emerg Infect Dis Dispatch We performed a molecular epidemiologic survey of mutations associated with drug-resistance genes in Plasmodium falciparum in northeastern Myanmar. In this region, 3 highly mutated drug-resistance haplotypes and 1 associated with decreased quinine susceptibility were prevalent, which suggests that parasites may be resistant to multiple commonly used antimalarial drugs. Centers for Disease Control and Prevention 2011-03 /pmc/articles/PMC3166001/ /pubmed/21392443 http://dx.doi.org/10.3201/eid1703.100870 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Yang, Zhaoqing
Li, Chaoqun
Miao, Miao
Zhang, Zaixing
Sun, Xiaodong
Meng, Hao
Li, Jie
Fan, Qi
Cui, Liwang
Multidrug-Resistant Genotypes of Plasmodium falciparum, Myanmar
title Multidrug-Resistant Genotypes of Plasmodium falciparum, Myanmar
title_full Multidrug-Resistant Genotypes of Plasmodium falciparum, Myanmar
title_fullStr Multidrug-Resistant Genotypes of Plasmodium falciparum, Myanmar
title_full_unstemmed Multidrug-Resistant Genotypes of Plasmodium falciparum, Myanmar
title_short Multidrug-Resistant Genotypes of Plasmodium falciparum, Myanmar
title_sort multidrug-resistant genotypes of plasmodium falciparum, myanmar
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166001/
https://www.ncbi.nlm.nih.gov/pubmed/21392443
http://dx.doi.org/10.3201/eid1703.100870
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