Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa

We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008–April 2009, 13 (68%) had isolates resistant to all 8 drugs tes...

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Autores principales: Shah, N. Sarita, Richardson, Jessica, Moodley, Prashini, Moodley, Salona, Babaria, Palav, Ramtahal, Melissa, Heysell, Scott K., Li, Xuan, Moll, Anthony P., Friedland, Gerald, Sturm, A. Willem, Gandhi, Neel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2011
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166021/
https://www.ncbi.nlm.nih.gov/pubmed/21392446
http://dx.doi.org/10.3201/eid1703.101363
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author Shah, N. Sarita
Richardson, Jessica
Moodley, Prashini
Moodley, Salona
Babaria, Palav
Ramtahal, Melissa
Heysell, Scott K.
Li, Xuan
Moll, Anthony P.
Friedland, Gerald
Sturm, A. Willem
Gandhi, Neel R.
author_facet Shah, N. Sarita
Richardson, Jessica
Moodley, Prashini
Moodley, Salona
Babaria, Palav
Ramtahal, Melissa
Heysell, Scott K.
Li, Xuan
Moll, Anthony P.
Friedland, Gerald
Sturm, A. Willem
Gandhi, Neel R.
author_sort Shah, N. Sarita
collection PubMed
description We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008–April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.
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spelling pubmed-31660212011-11-15 Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa Shah, N. Sarita Richardson, Jessica Moodley, Prashini Moodley, Salona Babaria, Palav Ramtahal, Melissa Heysell, Scott K. Li, Xuan Moll, Anthony P. Friedland, Gerald Sturm, A. Willem Gandhi, Neel R. Emerg Infect Dis Dispatch We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008–April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa. Centers for Disease Control and Prevention 2011-03 /pmc/articles/PMC3166021/ /pubmed/21392446 http://dx.doi.org/10.3201/eid1703.101363 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Shah, N. Sarita
Richardson, Jessica
Moodley, Prashini
Moodley, Salona
Babaria, Palav
Ramtahal, Melissa
Heysell, Scott K.
Li, Xuan
Moll, Anthony P.
Friedland, Gerald
Sturm, A. Willem
Gandhi, Neel R.
Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_full Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_fullStr Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_full_unstemmed Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_short Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa
title_sort increasing drug resistance in extensively drug-resistant tuberculosis, south africa
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166021/
https://www.ncbi.nlm.nih.gov/pubmed/21392446
http://dx.doi.org/10.3201/eid1703.101363
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