Cargando…

Tuberculosis Outbreak Investigations in the United States, 2002–2008

To understand circumstances of tuberculosis transmission that strain public health resources, we systematically reviewed Centers for Disease Control and Prevention (CDC) staff reports of US outbreaks in which CDC participated during 2002–2008 that involved >3 culture-confirmed tuberculosis cases...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitruka, Kiren, Oeltmann, John E., Ijaz, Kashef, Haddad, Maryam B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166029/
https://www.ncbi.nlm.nih.gov/pubmed/21392433
http://dx.doi.org/10.3201/eid1703.101550
_version_ 1782211108397907968
author Mitruka, Kiren
Oeltmann, John E.
Ijaz, Kashef
Haddad, Maryam B.
author_facet Mitruka, Kiren
Oeltmann, John E.
Ijaz, Kashef
Haddad, Maryam B.
author_sort Mitruka, Kiren
collection PubMed
description To understand circumstances of tuberculosis transmission that strain public health resources, we systematically reviewed Centers for Disease Control and Prevention (CDC) staff reports of US outbreaks in which CDC participated during 2002–2008 that involved >3 culture-confirmed tuberculosis cases linked by genotype and epidemiology. Twenty-seven outbreaks, representing 398 patients, were reviewed. Twenty-four of the 27 outbreaks involved primarily US-born patients; substance abuse was another predominant feature of outbreaks. Prolonged infectiousness because of provider- and patient-related factors was common. In 17 outbreaks, a drug house was a notable contributing factor. The most frequently documented intervention to control the outbreak was prioritizing contacts according to risk for infection and disease progression to ensure that the highest risk contacts were completely evaluated. US-born persons with reported substance abuse most strongly characterized the tuberculosis outbreaks in this review. Substance abuse remains one of the greatest challenges to controlling tuberculosis transmission in the United States.
format Online
Article
Text
id pubmed-3166029
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-31660292011-11-15 Tuberculosis Outbreak Investigations in the United States, 2002–2008 Mitruka, Kiren Oeltmann, John E. Ijaz, Kashef Haddad, Maryam B. Emerg Infect Dis Research To understand circumstances of tuberculosis transmission that strain public health resources, we systematically reviewed Centers for Disease Control and Prevention (CDC) staff reports of US outbreaks in which CDC participated during 2002–2008 that involved >3 culture-confirmed tuberculosis cases linked by genotype and epidemiology. Twenty-seven outbreaks, representing 398 patients, were reviewed. Twenty-four of the 27 outbreaks involved primarily US-born patients; substance abuse was another predominant feature of outbreaks. Prolonged infectiousness because of provider- and patient-related factors was common. In 17 outbreaks, a drug house was a notable contributing factor. The most frequently documented intervention to control the outbreak was prioritizing contacts according to risk for infection and disease progression to ensure that the highest risk contacts were completely evaluated. US-born persons with reported substance abuse most strongly characterized the tuberculosis outbreaks in this review. Substance abuse remains one of the greatest challenges to controlling tuberculosis transmission in the United States. Centers for Disease Control and Prevention 2011-03 /pmc/articles/PMC3166029/ /pubmed/21392433 http://dx.doi.org/10.3201/eid1703.101550 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Mitruka, Kiren
Oeltmann, John E.
Ijaz, Kashef
Haddad, Maryam B.
Tuberculosis Outbreak Investigations in the United States, 2002–2008
title Tuberculosis Outbreak Investigations in the United States, 2002–2008
title_full Tuberculosis Outbreak Investigations in the United States, 2002–2008
title_fullStr Tuberculosis Outbreak Investigations in the United States, 2002–2008
title_full_unstemmed Tuberculosis Outbreak Investigations in the United States, 2002–2008
title_short Tuberculosis Outbreak Investigations in the United States, 2002–2008
title_sort tuberculosis outbreak investigations in the united states, 2002–2008
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166029/
https://www.ncbi.nlm.nih.gov/pubmed/21392433
http://dx.doi.org/10.3201/eid1703.101550
work_keys_str_mv AT mitrukakiren tuberculosisoutbreakinvestigationsintheunitedstates20022008
AT oeltmannjohne tuberculosisoutbreakinvestigationsintheunitedstates20022008
AT ijazkashef tuberculosisoutbreakinvestigationsintheunitedstates20022008
AT haddadmaryamb tuberculosisoutbreakinvestigationsintheunitedstates20022008