N-Acetylcysteine and Allopurinol Synergistically Enhance Cardiac Adiponectin Content and Reduce Myocardial Reperfusion Injury in Diabetic Rats

BACKGROUND: Hyperglycemia-induced oxidative stress plays a central role in the development of diabetic myocardial complications. Adiponectin (APN), an adipokine with anti-diabetic and anti-ischemic effects, is decreased in diabetes. It is unknown whether or not antioxidant treatment with N-acetylcys...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Qiao, Shigang, Lei, Shaoqing, Liu, Yanan, Ng, Kwok F. J., Xu, Aimin, Lam, Karen S. L., Irwin, Michael G., Xia, Zhengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166050/
https://www.ncbi.nlm.nih.gov/pubmed/21912612
http://dx.doi.org/10.1371/journal.pone.0023967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166050/
https://www.ncbi.nlm.nih.gov/pubmed/21912612
http://dx.doi.org/10.1371/journal.pone.0023967

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