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N-Acetylcysteine and Allopurinol Synergistically Enhance Cardiac Adiponectin Content and Reduce Myocardial Reperfusion Injury in Diabetic Rats
BACKGROUND: Hyperglycemia-induced oxidative stress plays a central role in the development of diabetic myocardial complications. Adiponectin (APN), an adipokine with anti-diabetic and anti-ischemic effects, is decreased in diabetes. It is unknown whether or not antioxidant treatment with N-acetylcys...
Autores principales: | Wang, Tingting, Qiao, Shigang, Lei, Shaoqing, Liu, Yanan, Ng, Kwok F. J., Xu, Aimin, Lam, Karen S. L., Irwin, Michael G., Xia, Zhengyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166050/ https://www.ncbi.nlm.nih.gov/pubmed/21912612 http://dx.doi.org/10.1371/journal.pone.0023967 |
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