Identification of KIF3A as a Novel Candidate Gene for Childhood Asthma Using RNA Expression and Population Allelic Frequencies Differences

BACKGROUND: Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene association studies in asthma is the selection of biologically relevant genes. METHODOLOGY/PRINCIPAL FINDINGS: Using epithelial RNA expression arrays, HapMap allele frequen...

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Detalles Bibliográficos
Autores principales: Butsch Kovacic, Melinda, Biagini Myers, Jocelyn M., Wang, Ning, Martin, Lisa J., Lindsey, Mark, Ericksen, Mark B., He, Hua, Patterson, Tia L., Baye, Tesfaye M., Torgerson, Dara, Roth, Lindsey A., Gupta, Jayanta, Sivaprasad, Umasundari, Gibson, Aaron M., Tsoras, Anna M., Hu, Donglei, Eng, Celeste, Chapela, Rocío, Rodríguez-Santana, José R., Rodríguez-Cintrón, William, Avila, Pedro C., Beckman, Kenneth, Seibold, Max A., Gignoux, Chris, Musaad, Salma M., Chen, Weiguo, Burchard, Esteban González, Khurana Hershey, Gurjit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166061/
https://www.ncbi.nlm.nih.gov/pubmed/21912604
http://dx.doi.org/10.1371/journal.pone.0023714

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