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Impact of Host Genes and Strand Selection on miRNA and miRNA* Expression
Dysregulation of miRNAs expression plays a critical role in the pathogenesis of genetic, multifactorial disorders and in human cancers. We exploited sequence, genomic and expression information to investigate two main aspects of post-transcriptional regulation in miRNA biogenesis, namely strand sele...
Autores principales: | Biasiolo, Marta, Sales, Gabriele, Lionetti, Marta, Agnelli, Luca, Todoerti, Katia, Bisognin, Andrea, Coppe, Alessandro, Romualdi, Chiara, Neri, Antonino, Bortoluzzi, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166117/ https://www.ncbi.nlm.nih.gov/pubmed/21909367 http://dx.doi.org/10.1371/journal.pone.0023854 |
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