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Tree-Based Position Weight Matrix Approach to Model Transcription Factor Binding Site Profiles
Most of the position weight matrix (PWM) based bioinformatics methods developed to predict transcription factor binding sites (TFBS) assume each nucleotide in the sequence motif contributes independently to the interaction between protein and DNA sequence, usually producing high false positive predi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166302/ https://www.ncbi.nlm.nih.gov/pubmed/21912677 http://dx.doi.org/10.1371/journal.pone.0024210 |