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Tree-Based Position Weight Matrix Approach to Model Transcription Factor Binding Site Profiles

Most of the position weight matrix (PWM) based bioinformatics methods developed to predict transcription factor binding sites (TFBS) assume each nucleotide in the sequence motif contributes independently to the interaction between protein and DNA sequence, usually producing high false positive predi...

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Detalles Bibliográficos
Autores principales:	Bi, Yingtao, Kim, Hyunsoo, Gupta, Ravi, Davuluri, Ramana V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166302/ https://www.ncbi.nlm.nih.gov/pubmed/21912677 http://dx.doi.org/10.1371/journal.pone.0024210

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