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Ranking Candidate Disease Genes from Gene Expression and Protein Interaction: A Katz-Centrality Based Approach
Many diseases have complex genetic causes, where a set of alleles can affect the propensity of getting the disease. The identification of such disease genes is important to understand the mechanistic and evolutionary aspects of pathogenesis, improve diagnosis and treatment of the disease, and aid in...
Autores principales: | Zhao, Jing, Yang, Ting-Hong, Huang, Yongxu, Holme, Petter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166320/ https://www.ncbi.nlm.nih.gov/pubmed/21912686 http://dx.doi.org/10.1371/journal.pone.0024306 |
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