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Ranking Candidate Disease Genes from Gene Expression and Protein Interaction: A Katz-Centrality Based Approach

Many diseases have complex genetic causes, where a set of alleles can affect the propensity of getting the disease. The identification of such disease genes is important to understand the mechanistic and evolutionary aspects of pathogenesis, improve diagnosis and treatment of the disease, and aid in...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Yang, Ting-Hong, Huang, Yongxu, Holme, Petter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166320/
https://www.ncbi.nlm.nih.gov/pubmed/21912686
http://dx.doi.org/10.1371/journal.pone.0024306

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