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Somatostatin Receptor 1 and 5 Double Knockout Mice Mimic Neurochemical Changes of Huntington's Disease Transgenic Mice

BACKGROUND: Selective degeneration of medium spiny neurons and preservation of medium sized aspiny interneurons in striatum has been implicated in excitotoxicity and pathophysiology of Huntington's disease (HD). However, the molecular mechanism for the selective sparing of medium sized aspiny n...

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Detalles Bibliográficos
Autores principales:	Rajput, Padmesh S., Kharmate, Geetanjali, Norman, Michael, Liu, Shi-He, Sastry, Bhagavatula R., Brunicardi, Charles F., Kumar, Ujendra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166321/ https://www.ncbi.nlm.nih.gov/pubmed/21912697 http://dx.doi.org/10.1371/journal.pone.0024467

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