Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival

Hypoxia is one of the features of poorly vascularised areas of solid tumours but cancer cells can survive in these areas despite the low oxygen tension. The adaptation to hypoxia requires both biochemical and genetic responses that culminate in a metabolic rearrangement to counter-balance the decrea...

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Detalles Bibliográficos
Autores principales: Frezza, Christian, Zheng, Liang, Tennant, Daniel A., Papkovsky, Dmitri B., Hedley, Barbara A., Kalna, Gabriela, Watson, David G., Gottlieb, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166325/
https://www.ncbi.nlm.nih.gov/pubmed/21912692
http://dx.doi.org/10.1371/journal.pone.0024411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166325/
https://www.ncbi.nlm.nih.gov/pubmed/21912692
http://dx.doi.org/10.1371/journal.pone.0024411

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