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Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival
Hypoxia is one of the features of poorly vascularised areas of solid tumours but cancer cells can survive in these areas despite the low oxygen tension. The adaptation to hypoxia requires both biochemical and genetic responses that culminate in a metabolic rearrangement to counter-balance the decrea...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166325/ https://www.ncbi.nlm.nih.gov/pubmed/21912692 http://dx.doi.org/10.1371/journal.pone.0024411 |