MiR-224 Targets the 3′UTR of Type 1 5′-Iodothyronine Deiodinase Possibly Contributing to Tissue Hypothyroidism in Renal Cancer

Type 1 iodothyronine deiodinase (DIO1) catalyses the conversion of prohormone thyroxine to the active thyroid hormone 3,3′,5-triiodothyronine (T3), important regulator of cell proliferation and differentiation. DIO1 expression is reduced in the most common type of kidney neoplasia, clear cell Renal...

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Detalles Bibliográficos
Autores principales: Boguslawska, Joanna, Wojcicka, Anna, Piekielko-Witkowska, Agnieszka, Master, Adam, Nauman, Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166326/
https://www.ncbi.nlm.nih.gov/pubmed/21912701
http://dx.doi.org/10.1371/journal.pone.0024541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166326/
https://www.ncbi.nlm.nih.gov/pubmed/21912701
http://dx.doi.org/10.1371/journal.pone.0024541

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