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MiR-224 Targets the 3′UTR of Type 1 5′-Iodothyronine Deiodinase Possibly Contributing to Tissue Hypothyroidism in Renal Cancer
Type 1 iodothyronine deiodinase (DIO1) catalyses the conversion of prohormone thyroxine to the active thyroid hormone 3,3′,5-triiodothyronine (T3), important regulator of cell proliferation and differentiation. DIO1 expression is reduced in the most common type of kidney neoplasia, clear cell Renal...
Autores principales: | Boguslawska, Joanna, Wojcicka, Anna, Piekielko-Witkowska, Agnieszka, Master, Adam, Nauman, Alicja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166326/ https://www.ncbi.nlm.nih.gov/pubmed/21912701 http://dx.doi.org/10.1371/journal.pone.0024541 |
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