Cargando…
Activation of Nrf2-Regulated Glutathione Pathway Genes by Ischemic Preconditioning
Prophylactic pharmacological activation of astrocytic gene expression driven by the transcription factor Nrf2 boosts antioxidant defences and protects against neuronal loss in ischemia and other disease models. However, the role of Nrf2 in mediating endogenous neuroprotective responses is less clear...
Autores principales: | Bell, Karen F. S., Fowler, Jill H., Al-Mubarak, Bashayer, Horsburgh, Karen, Hardingham, Giles E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166574/ https://www.ncbi.nlm.nih.gov/pubmed/21904646 http://dx.doi.org/10.1155/2011/689524 |
Ejemplares similares
-
Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment
por: Sigfridsson, Emma, et al.
Publicado: (2020) -
Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion
por: Sigfridsson, Emma, et al.
Publicado: (2018) -
Targeted de-repression of neuronal Nrf2 inhibits α-synuclein accumulation
por: Baxter, Paul S., et al.
Publicado: (2021) -
The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults
por: Martel, Marc-André, et al.
Publicado: (2012) -
Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress
por: Al-Mubarak, Bashayer R., et al.
Publicado: (2021)