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Acetaldehyde-Mediated Neurotoxicity: Relevance to Fetal Alcohol Spectrum Disorders

Ethanol-induced neuro-developmental abnormalities are associated with impaired insulin and IGF signaling, and increased oxidative stress in CNS neurons. We examined the roles of ethanol and its principal toxic metabolite, acetaldehyde, as mediators of impaired insulin/IGF signaling and oxidative inj...

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Detalles Bibliográficos
Autores principales:	Tong, Ming, Longato, Lisa, Nguyen, Quynh-Giao/Ly, Chen, William C., Spaisman, Amy, de la Monte, Suzanne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166768/ http://dx.doi.org/10.1155/2011/213286

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