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Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway
To maintain an intact barrier, epithelia eliminate dying cells by extrusion. During extrusion, a cell destined for apoptosis signals its neighboring cells to form and contract a ring of actin and myosin, which squeezes the dying cell out of the epithelium. Here, we demonstrate that the signal produc...
Autores principales: | Gu, Yapeng, Forostyan, Tetyana, Sabbadini, Roger, Rosenblatt, Jody |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166871/ https://www.ncbi.nlm.nih.gov/pubmed/21555463 http://dx.doi.org/10.1083/jcb.201010075 |
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