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The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys

BACKGROUND: Activation of the peroxisome proliferator-activated receptor gamma (PPAR-γ) has been proposed as a possible neuroprotective strategy to slow down the progression of early Parkinson's disease (PD). Here we report preclinical data on the use of the PPAR-γ agonist pioglitazone (Actos(®...

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Detalles Bibliográficos
Autores principales:	Swanson, Christine R, Joers, Valerie, Bondarenko, Viktoriya, Brunner, Kevin, Simmons, Heather A, Ziegler, Toni E, Kemnitz, Joseph W, Johnson, Jeffrey A, Emborg, Marina E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166925/ https://www.ncbi.nlm.nih.gov/pubmed/21819568 http://dx.doi.org/10.1186/1742-2094-8-91

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