Cargando…

In vitro generation of human cells with cancer stem cell properties

Cancer stem cells (CSCs) have been implicated in the maintenance and progression of several types of cancer. The origin and cellular properties of human CSCs are poorly characterized. Here we show that CSC-like cells can be generated in vitro by oncogenic reprogramming of human somatic cells during...

Descripción completa

Detalles Bibliográficos
Autores principales: Scaffidi, Paola, Misteli, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166977/
https://www.ncbi.nlm.nih.gov/pubmed/21857669
http://dx.doi.org/10.1038/ncb2308