Targeted Intestinal Epithelial Deletion of the Chemokine Receptor CXCR4 Reveals Key Roles for Extracellular-Regulated Kinase-1/2 in Restitution

Barrier defects and/or alterations in the ability of the gut epithelium to repair itself are critical etiologic mechanisms of gastrointestinal disease. Our ongoing studies indicate that the chemokine receptor CXCR4 and its cognate ligand CXCL12 regulate intestinal epithelial barrier maturation and r...

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Detalles Bibliográficos
Autores principales: Zimmerman, Noah P., Vongsa, Rebecca A., Faherty, Sheena L., Salzman, Nita H., Dwinell, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167207/
https://www.ncbi.nlm.nih.gov/pubmed/21537329
http://dx.doi.org/10.1038/labinvest.2011.77

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