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p53 and telomerase control rat myocardial tissue response to hypoxia and ageing

Cellular senescence implies loss of proliferative and tissue regenerative capability. Also hypoxia, producing Reactive Oxygen Species (ROS), can damage cellular components through the oxidation of DNA, proteins and lipids, thus influencing the shortening of telomeres. Since ribonucleoprotein Telomer...

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Detalles Bibliográficos
Autores principales:	Cataldi, A., Zara, S., Rapino, M., Zingariello, M., di Giacomo, V., Antonucci, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PAGEPress Publications 2009
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167339/ https://www.ncbi.nlm.nih.gov/pubmed/22073357 http://dx.doi.org/10.4081/ejh.2009.e25

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