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Inferring causative variants in microRNA target sites

MicroRNAs (miRNAs) regulate genes post transcription by pairing with messenger RNA (mRNA). Variants such as single nucleotide polymorphisms (SNPs) in miRNA regulatory regions might result in altered protein levels and disease. Genome-wide association studies (GWAS) aim at identifying genomic regions...

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Detalles Bibliográficos
Autores principales: Thomas, Laurent F., Saito, Takaya, Sætrom, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167593/
https://www.ncbi.nlm.nih.gov/pubmed/21693556
http://dx.doi.org/10.1093/nar/gkr414