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Gene amplification system based on double rolling-circle replication as a model for oncogene-type amplification
Gene amplification contributes to a variety of biological phenomena, including malignant progression and drug resistance. However, details of the molecular mechanisms remain to be determined. Here, we have developed a gene amplification system in yeast and mammalian cells that is based on double rol...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167607/ https://www.ncbi.nlm.nih.gov/pubmed/21653557 http://dx.doi.org/10.1093/nar/gkr442 |