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Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication

DNA polymerase I (pol I) processes RNA primers during lagging-strand synthesis and fills small gaps during DNA repair reactions. However, it is unclear how pol I and pol III work together during replication and repair or how extensive pol I processing of Okazaki fragments is in vivo. Here, we addres...

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Detalles Bibliográficos
Autores principales:	Allen, Jennifer M., Simcha, David M., Ericson, Nolan G., Alexander, David L., Marquette, Jacob T., Van Biber, Benjamin P., Troll, Chris J., Karchin, Rachel, Bielas, Jason H., Loeb, Lawrence A., Camps, Manel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167613/ https://www.ncbi.nlm.nih.gov/pubmed/21622658 http://dx.doi.org/10.1093/nar/gkr157

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