G4 Resolvase 1 tightly binds and unwinds unimolecular G4-DNA

It has been previously shown that the DHX36 gene product, G4R1/RHAU, tightly binds tetramolecular G4-DNA with high affinity and resolves these structures into single strands. Here, we test the ability of G4R1/RHAU to bind and unwind unimolecular G4-DNA. Gel mobility shift assays were used to measure...

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Detalles Bibliográficos
Autores principales: Giri, Banabihari, Smaldino, Philip J., Thys, Ryan G., Creacy, Steven D., Routh, Eric D., Hantgan, Roy R., Lattmann, Simon, Nagamine, Yoshikuni, Akman, Steven A., Vaughn, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167620/
https://www.ncbi.nlm.nih.gov/pubmed/21586581
http://dx.doi.org/10.1093/nar/gkr234

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