Relationships between Membrane Binding, Affinity and Cell Internalization Efficacy of a Cell-Penetrating Peptide: Penetratin as a Case Study

BACKGROUND: Penetratin is a positively charged cell-penetrating peptide (CPP) that has the ability to bind negatively charged membrane components, such as glycosaminoglycans and anionic lipids. Whether this primary interaction of penetratin with these cell surface components implies that the peptide...

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Detalles Bibliográficos
Autores principales: Alves, Isabel D., Bechara, Cherine, Walrant, Astrid, Zaltsman, Yefim, Jiao, Chen-Yu, Sagan, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167814/
https://www.ncbi.nlm.nih.gov/pubmed/21915283
http://dx.doi.org/10.1371/journal.pone.0024096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167814/
https://www.ncbi.nlm.nih.gov/pubmed/21915283
http://dx.doi.org/10.1371/journal.pone.0024096

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