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A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death
Nucleic acid aptamers have been developed as high-affinity ligands that may act as antagonists of disease-associated proteins. Aptamers are non immunogenic and characterised by high specificity and low toxicity thus representing a valid alternative to antibodies or soluble ligand receptor traps/deco...
Autores principales: | Esposito, Carla Lucia, Passaro, Diana, Longobardo, Immacolata, Condorelli, Gerolama, Marotta, Pina, Affuso, Andrea, de Franciscis, Vittorio, Cerchia, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167817/ https://www.ncbi.nlm.nih.gov/pubmed/21915281 http://dx.doi.org/10.1371/journal.pone.0024071 |
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