Cargando…

Enhanced Transferrin Receptor Expression by Proinflammatory Cytokines in Enterocytes as a Means for Local Delivery of Drugs to Inflamed Gut Mucosa

Therapeutic intervention in inflammatory bowel diseases (IBDs) is often associated with adverse effects related to drug distribution into non-diseased tissues, a situation which attracts a rational design of a targeted treatment confined to the inflamed mucosa. Upon activation of immune cells, trans...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harel, Efrat, Rubinstein, Abraham, Nissan, Aviram, Khazanov, Elena, Nadler Milbauer, Mirela, Barenholz, Yechezkel, Tirosh, Boaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167832/ https://www.ncbi.nlm.nih.gov/pubmed/21915296 http://dx.doi.org/10.1371/journal.pone.0024202

Ejemplares similares

The Anti-Inflammatory Activity of a Novel Fused-Cyclopentenone Phosphonate and Its Potential in the Local Treatment of Experimental Colitis
por: Moradov, Dorit, et al.
Publicado: (2015)

Reduction of Experimental Cerebral Malaria and Its Related Proinflammatory Responses by the Novel Liposome-Based β-Methasone Nanodrug
por: Guo, Jintao, et al.
Publicado: (2014)

Rivastigmine Alleviates Experimentally Induced Colitis in Mice and Rats by Acting at Central and Peripheral Sites to Modulate Immune Responses
por: Shifrin, Helena, et al.
Publicado: (2013)

Inflammation Is Present, Persistent and More Sensitive to Proinflammatory Triggers in Celiac Disease Enterocytes
por: Porpora, Monia, et al.
Publicado: (2022)

ProInflam: a webserver for the prediction of proinflammatory antigenicity of peptides and proteins
por: Gupta, Sudheer, et al.
Publicado: (2016)

Enterocyte-Based Bioassay via Quantitative Combination of Proinflammatory Sentinels Specific to 8-keto-trichothecenes
por: Park, Seong-Hwan, et al.
Publicado: (2020)

Novel histological repertoire of crypt-associated anomalies in inflamed colon mucosa
por: Rubio, Carlos A, et al.
Publicado: (2023)

Macrophage–endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa
por: Ren, Xingsheng, et al.
Publicado: (2023)

Tissue Factor and Tissue Factor Pathway Inhibitor in Chronically Inflamed Gallbladder Mucosa
por: Liczko, Jacek, et al.
Publicado: (2014)

REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation
por: van Beelen Granlund, Atle, et al.
Publicado: (2013)

Development of a Primary Human Co-Culture Model of Inflamed Airway Mucosa
por: Yonker, Lael M., et al.
Publicado: (2017)

Dynamic, Transient, and Robust Increase in the Innervation of the Inflamed Mucosa in Inflammatory Bowel Diseases
por: Gonzalez Acera, Miguel, et al.
Publicado: (2021)

A Case of Granulomatosis with Polyangiitis (Wegener's Granulomatosis) Presenting with Marked Inflamed Tracheobronchial Mucosa
por: Nishiuma, Teruaki, et al.
Publicado: (2013)

CD73-Dependent Regulation of Interferon AlphaA and Interleukin-10 in the Inflamed Mucosa
por: Sotnikov, Ilya, et al.
Publicado: (2010)

MicroRNA exhibit altered expression in the inflamed colonic mucosa of ulcerative colitis patients
por: Valmiki, Swati, et al.
Publicado: (2017)

Bacterial Mucosa-associated Microbiome in Inflamed and Proximal Noninflamed Ileum of Patients With Crohn’s Disease
por: Olaisen, Maya, et al.
Publicado: (2020)

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease
por: Walker, Alan W, et al.
Publicado: (2011)

Folic Acid Supplementation Promotes Hypomethylation in Both the Inflamed Colonic Mucosa and Colitis-Associated Dysplasia
por: Chang, Wen-Chi L., et al.
Publicado: (2023)

Therapeutic Efficacy of Combining PEGylated Liposomal Doxorubicin and Radiofrequency (RF) Ablation: Comparison between Slow-Drug-Releasing, Non-Thermosensitive and Fast-Drug-Releasing, Thermosensitive Nano-Liposomes
por: Andriyanov, Alexander V., et al.
Publicado: (2014)

Nano-Drugs Based on Nano Sterically Stabilized Liposomes for the Treatment of Inflammatory Neurodegenerative Diseases
por: Turjeman, Keren, et al.
Publicado: (2015)

Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro
por: Neun, Barry W., et al.
Publicado: (2018)

Liposomal Bupivacaine (Bupigel) Demonstrates Minimal Local Nerve Toxicity in a Rabbit Functional Model
por: Bavli, Yaelle, et al.
Publicado: (2021)

Effect of e-cigarette aerosol on gingival mucosa structure and proinflammatory cytokine response
por: Alanazi, Humidah, et al.
Publicado: (2022)

Enterocytes in Food Hypersensitivity Reactions
por: Krstić Ristivojević, Maja, et al.
Publicado: (2021)

Multiplex gene expression profile in inflamed mucosa of patients with Crohn’s disease ileal localization: A pilot study
por: Giudici, Francesco, et al.
Publicado: (2019)

The Anti-inflammatory Immune Regulation Induced by Butyrate Is Impaired in Inflamed Intestinal Mucosa from Patients with Ulcerative Colitis
por: Magnusson, Maria K., et al.
Publicado: (2019)

Prevalence, Cell Tropism, and Clinical Impact of Human Parvovirus Persistence in Adenomatous, Cancerous, Inflamed, and Healthy Intestinal Mucosa
por: Xu, Man, et al.
Publicado: (2022)

Budesonide-Loaded Hyaluronic Acid Nanoparticles for Targeted Delivery to the Inflamed Intestinal Mucosa in a Rodent Model of Colitis
por: Vafaei, Seyed Yaser, et al.
Publicado: (2022)

Mulberry Biomass-Derived Nanomedicines Mitigate Colitis through Improved Inflamed Mucosa Accumulation and Intestinal Microenvironment Modulation
por: Yang, Wenjing, et al.
Publicado: (2023)

The colonic mucosa-associated microbiome in SIV infection: shift towards Bacteroidetes coincides with mucosal CD4(+) T cell depletion and enterocyte damage
por: Allers, Kristina, et al.
Publicado: (2020)

Reduced T Cell Receptor Excision Circle Levels in the Colonic Mucosa of Microscopic Colitis Patients Indicate Local Proliferation rather than Homing of Peripheral Lymphocytes to the Inflamed Mucosa
por: Kumawat, Ashok Kumar, et al.
Publicado: (2013)

Inflamed Eyes
por: Knaggs, R. Lawford
Publicado: (1894)

Inflamed Dentine
por: Smith, Henry A.
Publicado: (1857)

Inflamed Eyelids
Publicado: (1891)

Inflamed Eyelids
Publicado: (1891)

Multistep, effective drug distribution within solid tumors
por: Shemi, Amotz, et al.
Publicado: (2015)

Roadmap and strategy for overcoming infusion reactions to nanomedicines
por: Szebeni, Janos, et al.
Publicado: (2018)

Immunorthodontics: in vivo gene expression of orthodontic tooth movement
por: Klein, Yehuda, et al.
Publicado: (2020)

PEGylated Liposomes Remotely Loaded with the Combination of Doxorubicin, Quinine, and Indocyanine Green Enable Successful Treatment of Multidrug-Resistant Tumors
por: Grabarnick (Portnoy), Emma, et al.
Publicado: (2021)

Haemophilus parasuis Subunit Vaccines Based on Native Proteins with Affinity to Porcine Transferrin Prevent the Expression of Proinflammatory Chemokines and Cytokines in Pigs
por: Frandoloso, R., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_atsun719bebi65bc75j6urtluo