Modulation of Cellular Hsp72 Levels in Undifferentiated and Neuron-Like SH-SY5Y Cells Determines Resistance to Staurosporine-Induced Apoptosis

Increased expression of Hsp72 accompanies differentiation of human neuroblastoma SH-SY5Y cells to neuron-like cells. By modulating cellular levels of Hsp72, we demonstrate here its anti-apoptotic activity both in undifferentiated and neuron-like cells. Thermal preconditioning (43°C for 30 min) induc...

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Detalles Bibliográficos
Autores principales: Cheng, Lesley, Smith, Danielle J., Anderson, Robin L., Nagley, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167845/
https://www.ncbi.nlm.nih.gov/pubmed/21915333
http://dx.doi.org/10.1371/journal.pone.0024473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167845/
https://www.ncbi.nlm.nih.gov/pubmed/21915333
http://dx.doi.org/10.1371/journal.pone.0024473

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